Presenting a SARS-CoV-2 mouse model to study viral responses and vaccine candidates – EurekAlert

Researchers who generated a strain of SARS-CoV-2 that can infect mice used it to produce a new mouse model of infection that may help facilitate testing of COVID-19 vaccines and therapeutics. Notably, they used their mouse model to test and confirm the protective efficacy of a COVID-19 vaccine candidate. The ongoing COVID-19 pandemic has prioritized the development of small animal models for SARS-CoV-2. As SARS-CoV-2 does not use mouse ACE2 – the entry point for this virus in humans – mice are t…

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