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Polygenic risk score can predict risk of drug-induced liver injury – News-Medical.Net

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

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Reviewed by Emily Henderson, B.Sc.Sep 7 2020
Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.
Their study published Sept. 7, 2020, in Nature Medicine, reports identifying a “polygenic risk score” that shows when a drug, be it an approved medication or an experimental one, poses a risk of drug-induced liver injury (DILI).
The work was conducted by consortium of scientists …

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