Connect with us

Health

Pervasive lesion segregation shapes cancer genome evolution – Nature.com

Mutagenic lesions such as those that give rise to cancer frequently segregate—unrepaired—during cell division, resulting in phasing of multiple alleles across generations of daughter cells and consequent tumour heterogeneity.

Published

on

  • 1.Martincorena, I. et al. Universal patterns of selection in cancer and somatic tissues. Cell171, 10291041 (2017).
    CAS 
    PubMed 
    PubMed Central 
    Google Scholar 

  • 2.Turajlic…

    Click here to view the original article.

    Continue Reading
    Advertisement
    Advertisement

    Trending