Penrith Panthers make 16 changes as Ivan Cleary opts to rest stars with a combined 1,943 games of NRL experience

Penrith has left close to 2,000 games of first-grade experience on ice for its grudge match with Canterbury as it looks to become the first team from outside the top four to win a premiership in the NRL era.

After successive golden-point defeats to Melbourne and Canberra left the Panthers needing…