Health

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity – Nature.com

The papain-like protease PLpro is an essential coronavirus enzyme required for processing viral polyproteins to generate a functional replicase complex and enable viral spread1,2. PLpro is also implicated in cleaving proteinaceous post-translational modificat…

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5 years ago

July 29, 2020

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Institute of Biochemistry II, Faculty of Medicine, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany
Donghyuk Shin, Rukmini Mukherjee, Anshu Bhattacharya, Georg Tascher, Stefan Müller & Ivan Dikic

Buchmann Institute for Molecular Life Sciences, Goethe University, Max-von-Laue-Str. 15, 60438, Frankfurt am Main, Germany
Donghyuk Shin, Rukmini Mukherjee, Diana Grewe, Anshu Bhattacharya & Ivan Dikic

Max Planck Institute of Biophysics, Max-von…

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Related Topics:Australia Nature.com

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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity – Nature.com

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