‘Off switch’ during error-prone cell cycle phase may fix CRISPR problem – Phys.org

A group of researchers developed a promising fix to CRISPR-Cas9’s problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs are likely to happen.
Researchers from Hiroshima University and Tokyo Medical and Dental University published on Communications Biology the results of their study which successfully demonstrated a more precise gene-editing and suppressed unintended genetic deletions, insertions,…

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