Nutrition, companionship reduce pain in mice with sickle cell disease: Serotonin-boosting antidepressant duloxetine had same effect, could be opioid alternative – Science Daily

Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.”Finding safe and effective alternatives to opioids is a research priority, especially for patients with sickle cell disease,” said Dr. Keith Hoots,…

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