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New way to halt leukemia relapse shown promising in mice – EurekAlert

Drugs tackling chronic myelogenous leukemia have completely transformed prognoses of patients over the last couple of decades, with most cases going into remission. But drug resistance can occur, leading to relapses. Targeting the lipids involved in regulatin…

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IMAGE: CML stem cells, which are the cellular source of the vast majority of CML cells, are reportedly resistant to TKI therapy due to the stem cell quiescence. Thus, the remaining…
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Credit: Kazuhito Naka, Hiroshima University
Researchers have identified a second path to defeating chronic myelogenous leukemia, which tends to affect older adults, even in the face of resistance to existing drugs.
The new findings were published on September 17th in Nature Communications.
Almost …

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