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New insights on structural biology may help design more efficient antibodies – News-Medical.Net

In structural biology, some molecules are so unusual they can only be captured with a unique set of tools.

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In structural biology, some molecules are so unusual they can only be captured with a unique set of tools. That’s precisely how a multi-institutional research team led by Salk scientists defined how antibodies can recognize a compound called phosphohistidine–a highly unstable molecule that has been found to play a central role in some forms of cancer, such as liver and breast cancer and neuroblastoma.
These insights not only set up the researchers for more advanced studies on phosphohistidine and…

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