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New drug targets for lethal brain cancer discovered – Medical Xpress

More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke’s Hospital and their collaborators engineered a new mouse mod…

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More than 200 genes with novel and known roles in glioblastomathe most aggressive type of brain canceroffer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke’s Hospital and their collaborators engineered a new mouse model to show for the first time how a mutation in the well-known cancer gene, EGFR initiates glioblastoma, and works with a selection from more than 200 other genes to drive the cancer.
The results, published today in Genome Biology present the…

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