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New CRISPR system edits body’s response to prevent immunity against AAVs – Drug Target Review

A CRISPR system that suppresses AAV antibody production has been developed to prevent immunity against the gene therapy.

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Posted: 4 September 2020 | Victoria Rees (Drug Target Review) | No comments yet
A novel CRISPR system that suppresses genes related to adeno-associated virus (AAV) antibody production has been developed to prevent immunity against the gene therapy.
Researchers have created a new CRISPR system that suppresses genes related to adeno-associated virus (AAV) antibody production so that the virus can deliver its cargo unimpeded. 
According to the researchers from the University of Pittsburgh School…

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