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New clues why gold standard treatment for bipolar disorder doesn’t work for majority of patients – Hindustan Times

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 per cent of people with BD don’t respond to it. This leaves them at risk…

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Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 per cent of people with BD don’t respond to it. This leaves them at risk for debilitating, potentially life-threatening. Researchers at the Salk Institute have found that the culprit may lie in gene activity — or lack of it.
A new study led by Salk Professor and President Rusty Gage, which was published in the journal Molecular Psychiatry on January 4, 2021, shows that decreased activation of a gene called…

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