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New clues to classic cancer target found in immune cells – EurekAlert

New clues to a long-pursued drug target in cancer may reside within immune cells, researchers have discovered. The new findings not only shed new light on cancer…

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New clues to a long-pursued drug target in cancer may reside within immune cells, researchers at the University of Michigan Rogel Cancer Center have discovered.
The findings, which appear in Nature Immunology, not only shed new light on cancer immunology, they also suggest clinical trials related to this key target — an interaction that destabilizes the important p53 tumor suppressor protein — may unnecessarily be excluding a large number of patients.
The researchers are optimistic that the findings…

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