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Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function – News-Medical.Net

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

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The onset of the coronavirus disease 2019 (COVID-19) brought about intensive research on the biological characteristics of the pathogen responsible, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The immune response mediated by neutralizing antibodies, elicited by the virus or by vaccines, is of paramount importance in determining the type of intervention necessary to achieve population immunity, which is agreed to be the sole hope of arresting the pandemic and emerging from its…

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