Health
Naturally-Occurring Metabolite Increases Lifespan in Mice – Technology Networks
A metabolite produced by the body increases lifespan and dramatically compresses late-life morbidity in mice, according to new research.
Middle-aged mice that had the naturally-occurring metabolite alpha-ketaglutarate (AKG) added to their chow had a better old age. They were healthier as they aged and experienced a dramatically shorter time of disease and disability before they died, a first for research involving mammals. Results from the double-blinded study, published in Cell Metabolism, were based on clinically-relevant markers of healthspan.Previous studies show that blood plasma levels of AKG can drop up to 10-fold as we ag…
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