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Multi-center Phase I study of anti-VISTA opens for patient enrollment – News-Medical.Net

Dartmouth and Dartmouth-Hitchcock Norris Cotton Cancer Center will serve as one of the lead institutions for a new multi-center clinical trial of anti-VISTA, no…

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Reviewed by Emily Henderson, B.Sc.Oct 7 2020
Dartmouth and Dartmouth-Hitchcock Norris Cotton Cancer Center (NCCC) will serve as one of the lead institutions for a new multi-center clinical trial of anti-VISTA, now open and recruiting for patient enrollment. The trial is a Phase I study of CI-8993, an anti-VISTA (V-domain Ig Suppressor of T-cell Activation) antibody, in adult patients with advanced solid tumors.
VISTA is a checkpoint regulator whose function is to prevent activation of the immu…

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