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More than 40-year-old cancer mystery solved: Thanks to epigenetics – News-Medical.Net

In an article that was just published in Proceedings of the National Academy of Sciences by the group of Dr. Manel Esteller, is solved this mystery by describing that in cancer cells the protein that generates the nucleotide “Y” is epigenetically inactivated,…

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Reviewed by Emily Henderson, B.Sc.Aug 12 2020
In an article that was just published in Proceedings of the National Academy of Sciences (PNAS) by the group of Dr. Manel Esteller, is solved this mystery by describing that in cancer cells the protein that generates the nucleotide “Y” is epigenetically inactivated, causing small but highly aggressive tumors.
Before the first oncogene mutations were discovered in human cancer in the early 1980s, the 1970s provided the first data suggesting alterati…

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