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Mechano-immunological response to SARS-CoV-2 – News-Medical.Net

In a recent study, researchers demonstrated a human organ-on-a-chip (Organ Chip) microfluidic model of the lung alveolus (Alveolus Chip) – that recapitulates the…

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When influenza A viruses and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infect the human body, innate immune responses in the lung act as the first line of defense against these pathogens, however, little is known about how these responses are controlled locally within the physical microenvironment of the human breathing lung.
Because it is difficult to tease out the regulatory cues in the local environment within a living organ in vivo, and the mechanical cues experienced…

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