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MC3R Mutations Linked to Timing of Puberty – MedPage Today
Mutation found to be associated with delay in age at menarche and lower levels of IGF1
People who carry loss-of-function mutations in MC3R have later onset of puberty, researchers found.
Over 800 females carrying a MC3R mutation had a 4.7-month delay in age at menarche compared with non-carriers, reported Stephen O’Rahilly, MD, of the University…
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