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Mayo Clinic researchers develop test to measure effect of breast cancer gene variants – Newswise

Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene w

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Newswise — ROCHESTER, Minn. Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study in the American Journal of Human Genetics.
“There are 4,565 different VUS in the BRCA2 gene listed in the National…

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