Health
Master Regulator proteins control cancer transcriptional identity – News-Medical.Net
Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer’s origin,…
Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer’s origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer’s transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.
The study, published Jan. 11 in Cell, confirms that Master Regulators provide the molecular…
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