Health
Inherited genetic variant influences response to leukemia treatment for some children – EurekAlert
St. Jude researchers showed that an inherited variant of the GATA3 gene is tied to minimal residual disease levels and response to therapy for acute lymphoblastic leukemia.
IMAGE: Jun J. Yang, Ph.D., of St. Jude Pharmaceutical Sciences and Oncology
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Credit: St. Jude
Scientists at St. Jude Children’s Research Hospital are investigating the inherited genetics of childhood leukemia and how particular gene variations can affect treatment outcomes. The research showed that an inherited variation in the GATA3 gene strongly influences early response to chemotherapy and is linked to relapse in children with acute lymphoblastic leukemia (ALL). The work was pub…
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