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Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses – News-Medical.Net

Individuals with severe forms of COVID-19 disease can present with compromised type I interferon (IFN) responses based on their genetics, according to results published in two papers today in the journal Science.

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Reviewed by Emily Henderson, B.Sc.Sep 25 2020
Individuals with severe forms of COVID-19 disease can present with compromised type I interferon (IFN) responses based on their genetics, according to results published in two papers today in the journal Science. Type I IFN responses are critical for protecting cells and the body from more severe disease after acute viral infection.
In “Inborn errors of type I IFN immunity in patients with life-threatening COVID-19” and “Autoantibodies against type…

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