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Improving Sequencing Errors and Detection of Rare Mutations – Genetic Engineering & Biotechnology News

Researchers have developed a new technology to overcome the inefficiencies and high error rates common among next-generation sequencing techniques.

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There is little doubt within the scientific community of the immense impact that next-generation sequencing (NGS) has had on translational research. Techniques like liquid biopsy have allowed investigators to harness the power of NGS to identify genetic mutations from blood samples noninvasively. Identifying such mutations enables earlier diagnosis of cancer and can inform treatment decisions for many patients. However, NGS does not come without its own caveats, as high error rates are common among…

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