Health
Important structures of SARS-CoV-2 PLpro protease – News-Medical.Net
The pandemic of coronavirus disease 2019 (COVID-19) is changing the world like never before. This crisis is unlikely contained in the absence of effective therapeutics…
Reviewed by Emily Henderson, B.Sc.Oct 27 2020
The pandemic of coronavirus disease 2019 (COVID-19) is changing the world like never before. This crisis is unlikely contained in the absence of effective therapeutics or vaccine. The papain-like protease (PLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays essential roles in virus replication and immune evasion, presenting a promising drug target.
The authors of this paper determined two important structures of SARS-CoV-2 PLpro…
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