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Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates – Science Advances

Since the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), various vaccines are being developed, with most vaccine candidates focusing…

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INTRODUCTION
Coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is continuously spreading worldwide and has become a serious threat to global health. Therefore, an effective vaccine against SARS-CoV-2 is urgently needed, while only a handful have already been approved. The SARS-CoV-2 genome encodes four structural proteinsspike (S), membrane (M), envelope (E), and nucleocapsid (N) (1). Similar to the S protein of SARS-CoV, the S…

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