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Immune cell activation in severe COVID-19 resembles lupus: Extrafollicular B cell pathway – Science Daily

In severe cases of COVID-19, activation patterns of B cells resemble those seen in systemic lupus erythematosus, an autoimmune disease. Emory researchers want t…

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In severe cases of COVID-19, Emory researchers have been observing an exuberant activation of immune cells, resembling acute flares of systemic lupus erythematosus (SLE), an autoimmune disease.Their findings point towards tests that could separate some COVID-19 patients who need immune-calming therapies from others who may not. They also may begin to explain why some people infected with SARS-CoV-2 produce abundant antibodies against the virus, yet experience poor outcomes.
The results were pub…

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