Human Tumor Xenograft Models – News-Medical.net

In human tumor xenograft models, human tumor cells, collected by biopsy or cultured from a known cell line, are transplanted into immunocompromised mice that do not reject human cells, either under the skin (ectopic model) or into the organ type from which the tissue originated (orthotopic model). This allows researchers to assess the efficacy and safety of a drug or therapy towards a particular patient’s tumor in an in vivo setting.
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Following transplant,…

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