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How the vaginal microbiome may affect HIV prevention – EurekAlert

Healthy Lactobacillus bacteria in the vagina are critical for women’s health, but the accumulation of additional bacterial genera can imbalance the vaginal ecosystem….

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Healthy Lactobacillus bacteria in the vagina are critical for women’s health, but the accumulation of additional bacterial genera can imbalance the vaginal ecosystem. Such an imbalance may result in bacterial metabolism of drugs designed to prevent HIV infection, thereby decreasing their effectiveness and enhancing risks to women, according to a study published December 3, 2020 in the open-access journal PLOS Pathogens by Dr. Nichole Klatt of the University of Minnesota Medical School, and colleagues.

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