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How Could Nitric Oxide Treat Severe COVID-19? – News-Medical.net

Nitric oxide (NO) has the potential to be used to treat severe COVID-19 as it is a vasodilator, improving lung gas exchange and blood oxygenation.

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Nitric oxide (NO) has been used for decades in cases of acute respiratory distress syndrome (ARDS) as a vasodilator, improving gas exchange in the lungs and allowing the blood to better oxygenate.
NO is naturally produced by many cells of the body and plays an important role in signaling and homeostasis. It functions as a vasodilator by bonding with and activating the enzyme guanylate cyclase in the cytoplasm of vascular smooth muscle cells, leading to the production of cyclic-guanosine 3′,5′-monophosphate.

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