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How a protein stops cells from attacking their own DNA – Mirage News

Scientists at EPFL have demonstrated the mechanism that allows cells to fight off viral DNA without triggering an immune response against their own…

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Scientists at EPFL have demonstrated the mechanism that allows cells to fight off viral DNA without triggering an immune response against their own genetic material.Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway. The protein cyclic GMP-AMP Synthase (cGAS), which is also found inside the fluid, binds to the invading DNA to create a new molecule. This, in turn, bind…

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