Health
Host protein mimicry of SARS-CoV-2 receptor binding motif – News-Medical.Net
In a new study, structural bioinformatics approaches are employed to investigate the potential mimicry of the receptor-binding motif (RBM) of these three coronaviruses,…
Viruses frequently produce host protein mimics to stall or exploit cellular machinery within the replication cycle, and many such protein motifs have evolved to the capacity to enhance immune evasion. Coronavirus mimicry has been refined over many successive infections, with SARS-CoV-1, MERS-CoV, and SARS-CoV-2 encoding for many proteins that are homologous to those found in host cells.
In a paper recently uploaded to the bioRxiv* preprint server, structural bioinformatics approaches are employed…
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