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Ground-breaking films show RNA’s complex curves take shape – Nature.com

Experimental data and predictive algorithms combine to reveal the essential biomolecule’s shape-shifting.

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Every second, a myriad of shapeless strands of RNA fold, origami-style, into intricate structures inside living cells. Now, for the first time, researchers can watch a data-driven video of this folding as RNA molecules are made by the cellular machinery.
The 3D structure of an RNA molecule is tailored to its function, such as regulating gene expression. To visualize how RNA takes shape, Alan Chen at the University at Albany in New York, Julius Lucks at Northwestern University in Evanston, Illinois,…

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