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Genes That Best Predict Breast Cancer Risk Identified – HealthDay News
And estimates determined for breast cancer risk in association with pathogenic variants in known predisposition genes
FRIDAY, Feb. 5, 2021 (HealthDay News) — Certain genes and pathogenic variants of some of these genes confer predisposition to breast cancer, according to two studies published in the Feb. 4 issue of the New England Journal of Medicine.
Leila Dorling, Ph.D., from the University of Cambridge in the United Kingdom, and colleagues used a panel of 34 putative susceptibility genes to perform sequencing on samples from 60,466 women with breast cancer and 53,641 controls. The researchers found that protein-truncating…
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