Health
Found: a genetic link to molecular events that precede symptoms in Alzheimer’s disease – Newswise
Tufts researchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer’s disease-linked amyloid protei
Newswise — BOSTON (Nov. 18, 2020, 2:00 p.m. ET)—Researchers at Tufts University School of Medicine have discovered a molecular mechanism that causes a “traffic jam” of enzymes traveling up and down neuronal axons, leading to the accumulation of amyloid beta – a key feature and cause of Alzheimer’s disease. The enzyme, BACE1, gets backed up, causing the axons to clog and swell because of the increased production of the toxic amyloid protein.
The study, published today in Science Translational Medicine,…
-
General24 hours agoKim Nok-wan sentenced to life in prison for sexual abuse and exploitation of hundreds of people in South Korea
-
Noosa News19 hours agoQueensland teachers strike for second time this year after rejecting 8 per cent wage rise
-
General18 hours agoVictorian government blocked fire service from pursuing US giant over PFAS contamination
-
General22 hours agoXi Jinping tells Donald Trump Taiwan’s ‘return to China’ is key to international post-war order