Health
Found: a genetic link to molecular events that precede symptoms in Alzheimer’s disease – Newswise
Tufts researchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer’s disease-linked amyloid protei
Newswise — BOSTON (Nov. 18, 2020, 2:00 p.m. ET)—Researchers at Tufts University School of Medicine have discovered a molecular mechanism that causes a “traffic jam” of enzymes traveling up and down neuronal axons, leading to the accumulation of amyloid beta – a key feature and cause of Alzheimer’s disease. The enzyme, BACE1, gets backed up, causing the axons to clog and swell because of the increased production of the toxic amyloid protein.
The study, published today in Science Translational Medicine,…
-
General24 hours agoNew US tariffs on semiconductors coming ‘over the next week’, Donald Trump says
-
Noosa News24 hours agoPeter Dutton’s son ‘saving like mad’ to buy first home
-
Noosa News21 hours agoFather and son from the UK killed, local man in critical condition after Seventeen Seventy beach tragedy
-
General21 hours agoSearch for driver in Parramatta River after car hit woman before going into water