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Fortune or foresight? AstraZeneca and Oxford’s stories clash on COVID-19 vaccine – bdnews24.com

AstraZeneca and Oxford University have given conflicting accounts of how they came upon the most effective dosing pattern for their COVID-19 vaccine, a rare instance…

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The discrepancy, reported for the first time by Reuters, centres on the regimen administered to a smaller group of volunteers in the late-stage trials, of half a dose followed by a full dose. This diverged from the original plan of two full doses, given to the majority of participants.
The half-dose pattern was found to be 90% effective, versus the 62% success rate of the two-full-dose main study, based on interim data.
AstraZeneca’s research chief told Reuters 10 days ago, when interim trial data…

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