Health
Food for thought about the immune drivers of gut pain – Nature.com
Defence against bacterial infection can drive pain when eating food.
Pain evolved to alert us to and protect us from actual or potential tissue damage. There are three common forms: nociceptive pain, which is associated with the detection of damaging stimuli; inflammatory pain, associated with inflammation or infection; and chronic pain, which is a maladaptive, long-term form of pain1. Writing in Nature, Aguilera-Lizarraga et al.2 report evidence from mice and humans indicating a previously unknown mechanism that contributes to chronic gut pain.
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