Health
Extrathymic Aire-expressing cells support maternal-fetal tolerance – Science
The normal maternal immune system adapts to pregnancy by learning to tolerate both allogeneic paternal and pregnancy-associated…
Healthy pregnancy requires tolerance to fetal alloantigens as well as syngeneic embryonic and placental antigens. Given the importance of the autoimmune regulator (Aire) gene in self-tolerance, we investigated the role of Aire-expressing cells in maternal-fetal…
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