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Evolution may be to blame for high risk of advanced cancers in humans – Science Daily

Researchers discovered that most people no longer produce the Siglec-12 protein, but some of those who do are at twice the risk for advanced cancer.

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Compared to chimpanzees, our closest evolutionary cousins, humans are particularly prone to developing advanced carcinomas — the type of tumors that include prostate, breast, lung and colorectal cancers — even in the absence of known risk factors, such as genetic predisposition or tobacco use.A recent study led by researchers at University of California San Diego School of Medicine and Moores Cancer Center helps explain why. The study, published December 9, 2020 in FASEB BioAdvances, suggests…

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