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Engineering immunogens to focus immune response to SARS-CoV-2 – News-Medical.Net

Researchers have designed constructs by adding more glycans and adding the receptor-binding motif from related sarbecoviruses to focus the immune response to the…

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Researchers have designed constructs by adding more glycans and adding the receptor-binding motif from related sarbecoviruses to focus the immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding motif. Such immunogens could potentially also neutralize other variants and coronaviruses.
When infected by viruses, either by natural infection or vaccination, the human immune system responds by targeting glycoproteins on the virus’s surface. This can provide…

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