Health
Embedding clinical trials within routine health‐care delivery: Challenges and opportunities – Wiley
The COVID‐19 pandemic provides a pertinent reminder of the imperative to generate timely reliable clinical evidence. Delivery of optimal paediatric care is predicated…

Current medical guidelines rely on a highly variable evidence base, from highquality clinical trials to expert opinion. Currently, only 18% of Australian clinical guidelines addressing the top10 causes of mortality are based on level I (or equivalent) evidence.1 This shortfall must be addressed to optimise clinical outcomes for patients, with the benefit of economic and healthcare system efficiencies.
There is a significant cost associated with poor quality evidence in health care. US data suggest…
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