Health
Editing Immune Response to Boost Gene Therapy – Mirage News
Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In case of CRISPR-based gene therapies,…
Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body’s immune response to AAV can thwart the whole endeavor.
To overcome that obstacle, researchers at the University of Pittsburgh School of Medicine created a system that uses CRISPR in a different way. Their sy…
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