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Early, late stages of degenerative diseases are distinct: Two-phase theory applies to diseases like Alzheimer’s, Parkinson’s, muscle atrophy – Science Daily

Biochemists have proposed that degenerative diseases as varied as Alzheimer’s, Parkinson’s and muscle atrophy occur in two distinct phases marked by protein signaling…

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Rice University biochemists Michael Stern and James McNew have studied how neurodegeneration kills cells. They’ve conducted countless experiments over more than a decade, and they’ve summarized all they’ve learned in a simple diagram they hope may change how doctors perceive and treat degenerative diseases as varied as Alzheimer’s, Parkinson’s and muscle atrophy.In a study published this month in Molecular Psychiatry, McNew and Stern propose that degeneration, at the cellular level, occurs in two…

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