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Drugging RNA synthesis in SARS-CoV-2 as novel therapeutic avenue – News-Medical.Net

In a new study, the role of a coronavirus-specific protein domain in SARS-CoV-2 viral synthesis initiation is investigated, and potential therapeutic solutions…

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The initiation of viral RNA synthesis has evolved to take place by a wide variety of mechanisms, broadly categorized between primer-independent or primer-dependent. Considerable variation is observed within these categories, however, and the specific mechanisms directing the replication and transcription of viral RNA in coronaviruses have yet to be entirely elucidated.
In a paper recently uploaded to the bioRxiv* preprint server, the role of a coronavirus-specific protein domain in SARS-CoV-2 viral…

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