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Dexmedetomidine Ties Propofol for Intubated Adults With Sepsis – MedPage Today

No significant difference in days without delirium or coma

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Among mechanically ventilated adults with sepsis being treated with light sedation, no differences were observed between dexmedetomidine, an alpha-2 receptor agonist, and propofol, a randomized trial found.
There was no difference in days alive without delirium or coma between patients treated with dexmedetomidine versus propofol at 14 days (adjusted median 10.7 vs 10.8 days; OR 0.96, 95% CI 0.74-1.26), reported Christopher Hughes, MD, of Vanderbilt University Medical Center in Nashville, and colleagues.

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