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Designed antiviral proteins inhibit SARS-CoV-2 in the lab: Computer design of synthetic proteins is creating potent, stable antivirals that block infection at least as well as monoclonal antibodies – Science Daily

Computer-designed miniproteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. The lead antiviral candidate rivals the best-known SARS-CoV-2 monoclonal antibodies in its protective actions. The synth…

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Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.The findings are reported today, Sept. 9, in Science
In the experiments, the lead antiviral candidate, named LCB1, rivaled the best-known SARS-CoV-2 neutralizing antibodies in its protective actions. LCB1 is currently being evaluated in rodents.
Coronaviruses are studded with so-called Spike proteins. These latch onto human cells to enable the virus to bre…

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