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Crystal structures of nanobodies could aid the design of COVID-19 therapies – News-Medical.Net

Researchers at the National Institutes of Health in Bethesda, Maryland, have shown how certain synthetic nanobodies bind to the agent that causes coronavirus disease…

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Researchers at the National Institutes of Health in Bethesda, Maryland, have shown how certain synthetic nanobodies bind to the agent that causes coronavirus disease 2019 (COVID-19) – a development that could help inform the design of therapies.
The team describes the X-ray crystal structures of three synthetic nanobodies (sybodies) that bind to the receptor-binding domain (RBD) of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Superposing the structures onto models of the…

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