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Cryo-Electron Microscopy Reveals SARS-CoV-2 Surface Adopts 10 Different Structural States upon Contact with ACE2 – HospiMedica

The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor …

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The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to new research. This new insight into the mechanism of infection will equip research groups with the understanding needed to inform studies into vaccines and treatments. The surface of SARS-CoV-2, the virus that causes COVID-19, is covered in proteins called spikes, which enable the virus to infect human cells. The infect…

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