Cryo–electron microscopy breaks the atomic resolution barrier at last – Science Magazine

Cryoelectron microscopy reveals the atomic details of apoferritin, a hollow, spherically shaped protein complex that stores iron.
Paul Emsley/MRC Laboratory of Molecular Biology
By Robert F. ServiceOct. 21, 2020 , 11:00 AM
If you want to map the tiniest parts of a protein, you only have a few options: You can coax millions of individual protein molecules to align into crystals and analyze them using x-ray crystallography. Or you can flash-freeze copies of the protein and bombard them with electrons,…

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