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CRISPR screen identifies genes, drug targets to protect against SARS-CoV-2 infection – EurekAlert

Study demonstrates how changes in human genes can reduce SARS-CoV-2 infection and describes a wide array of genes that have not previously been considered as therapeutic…

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IMAGE: Graphical abstract of the Cell study
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Credit: Sanjana Lab of New York Genome Center/New York University
NEW YORK, NY (October 26, 2020) – To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome. The team examined which genetic modifications…

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